1382 Asymmetric cell divisions buffer against tissue overgrowth

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Control of Asymmetric Cell Divisions during Root Ground Tissue Maturation

Controlling the production of diverse cell/tissue types is essential for the development of multicellular organisms such as animals and plants. The Arabidopsis thaliana root, which contains distinct cells/tissues along longitudinal and radial axes, has served as an elegant model to investigate how genetic programs and environmental signals interact to produce different cell/tissue types. In the...

متن کامل

Symmetric vs. Asymmetric Stem Cell Divisions: An Adaptation against Cancer?

Traditionally, it has been held that a central characteristic of stem cells is their ability to divide asymmetrically. Recent advances in inducible genetic labeling provided ample evidence that symmetric stem cell divisions play an important role in adult mammalian homeostasis. It is well understood that the two types of cell divisions differ in terms of the stem cells' flexibility to expand wh...

متن کامل

Tugging and pulling in asymmetric cell divisions

Tugging and pulling in asymmetric cell divisions n asymmetric divisions, the cell alters the normal process that centers the spindle in the mother cell, but how it regulates the timing of spindle movement is unclear. Now, on page 245, Labbé et al. describe a tethering system that resists premature movement of the mitotic spindle during asymmetric cell divisions in C. elegans embryogenesis. It w...

متن کامل

Concise Review: Asymmetric Cell Divisions in Stem Cell Biology

Somatic stem cells are rare cells with unique properties residing in many organs and tissues. They are undifferentiated cells responsible for tissue regeneration and homeostasis, and contain both the capacity to self-renew in order to maintain their stem cell potential and to differentiate towards tissue-specific, specialized cells. However, the knowledge about the mechanisms controlling somati...

متن کامل

Text S1 The role of asymmetric stem cell divisions in tissue homeostasis

In the section we review the analysis of Komarova (2013) in the context of the present work, see also figure 3 of the main text. For the two-compartment model, we note that at least two of the four quantities, (qx, qy, px, py), must be nonzero to satisfy the stability condition: ∆ ≡ pyqx − pxqy > 0. In fact, there are exactly two cases where only two of the four derivatives are nonzero and sati...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Journal of Investigative Dermatology

سال: 2018

ISSN: 0022-202X

DOI: 10.1016/j.jid.2018.03.1399